Liver cancer incidence in the United States has tripled over the past four decades, and the American Cancer Society projects about 42,340 new cases and 30,980 deaths for 2026, yet five-year survival across all stages remains below 20% because most patients are diagnosed at intermediate or advanced stages. Surveillance could close much of this gap: fewer than one in four eligible patients receives any hepatocellular carcinoma surveillance, and fewer than 16% achieve the guideline-recommended semiannual ultrasound with AFP. Identifying every patient with cirrhosis or chronic viral hepatitis and documenting surveillance status precisely is among the highest-value clinical actions a primary care team can take.
AAVBC's Liver Cancer Quick Reference Guide equips primary care clinicians and care teams with a comprehensive, evidence-aligned reference covering ICD-10 coding specificity for hepatocellular carcinoma and metastatic liver disease, HCC/RAF V28 mapping, LI-RADS diagnostic thresholds and surveillance protocols, BCLC stage-aligned treatment, MEAT documentation standards, NCCN-aligned first-line systemic therapy, and comorbidity management for cirrhosis, viral hepatitis, and MASLD. Grounded in AASLD surveillance guidance and the BCLC staging framework, this guide supports consistent, individualized clinical decision-making, helping care teams close the surveillance gap and document disease status completely, with the clarity and continuity that durable outcomes require.
AAVBC’s Deep-Dive series offers a comprehensive, structured analysis of liver cancer — moving far beyond quick-reference essentials. These guides provide an integrated review of epidemiology, diagnostic strategy, staging, coding logic, MEAT-aligned documentation examples, treatment guidelines, review vulnerabilities, and cost-utilization considerations. The Deep-Dive combines evidence-informed clinical guidance with practical operational tools to support a deeper understanding of disease complexity and provide multidisciplinary teams with strategies to thrive within value-based frameworks.
Liver cancer incidence in the United States has tripled over the past four decades, and the American Cancer Society projects about 42,340 new cases and 30,980 deaths for 2026, yet five-year survival across all stages remains below 20% because most patients are diagnosed at intermediate or advanced stages. Surveillance could close much of this gap: fewer than one in four eligible patients receives any hepatocellular carcinoma surveillance, and fewer than 16% achieve the guideline-recommended semiannual ultrasound with AFP. Identifying every patient with cirrhosis or chronic viral hepatitis and documenting surveillance status precisely is among the highest-value clinical actions a primary care team can take.
AAVBC's Liver Cancer Quick Reference Guide equips primary care clinicians and care teams with a comprehensive, evidence-aligned reference covering ICD-10 coding specificity for hepatocellular carcinoma and metastatic liver disease, HCC/RAF V28 mapping, LI-RADS diagnostic thresholds and surveillance protocols, BCLC stage-aligned treatment, MEAT documentation standards, NCCN-aligned first-line systemic therapy, and comorbidity management for cirrhosis, viral hepatitis, and MASLD. Grounded in AASLD surveillance guidance and the BCLC staging framework, this guide supports consistent, individualized clinical decision-making, helping care teams close the surveillance gap and document disease status completely, with the clarity and continuity that durable outcomes require.
AAVBC’s Deep-Dive series offers a comprehensive, structured analysis of liver cancer — moving far beyond quick-reference essentials. These guides provide an integrated review of epidemiology, diagnostic strategy, staging, coding logic, MEAT-aligned documentation examples, treatment guidelines, review vulnerabilities, and cost-utilization considerations. The Deep-Dive combines evidence-informed clinical guidance with practical operational tools to support a deeper understanding of disease complexity and provide multidisciplinary teams with strategies to thrive within value-based frameworks.
